ODCs

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1 OMIM reference -
6 associated genes
12 signs/symptoms

PROTEIN INTERACTIONS: 1

1 OMIM reference -
1 associated gene
8 signs/symptoms

Peters anomaly

Hereditary cerebral hemorrhage with amyloidosis, Dutch type


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	TGFB2	(0.77)	APP

Citations in the biomedical literature:

Peters anomaly		Hereditary cerebral hemorrhage with amyloidosis, Dutch type
	Synonym(s): - Peters congenital glaucoma		Synonym(s): - HCHWA, Dutch type - HCHWA-D

	Classification (Orphanet): (no data available)		Classification (Orphanet): - Rare genetic disease - Rare neurologic disease - Rare systemic or rheumatologic disease

	Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -		Classification (ICD10): (no data available)

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: adulthood Average age of death: adult Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - 1 MeSH reference: C537884		External references: 1 OMIM reference - 2 MeSH references: C537944 / D028243

Peters anomaly		Hereditary cerebral hemorrhage with amyloidosis, Dutch type
	Very frequent - Anomalies of eyes and vision - Autosomal recessive inheritance - Microcornea Frequent - Corneal dystrophy Occasional - Anomalies of teeth and dentition - Anophthalmos / anophthalmia / microphthalmos / microphthalmia - Aphakia / microphakia / spherophakia / biphakia / absence of lens / lenticone / lentiglobus - Cataract / lens opacification - Corneal clouding / opacity / vascularisation - Dental malocclusion - Hypoplastic mandibula / partial absence of the mandibula - Nystagmus		Very frequent - Facial pain / cephalalgia / migraine - Intracranial / cerebral / meningeal hemorrhage - Psychic / behavioural troubles - Psychic / psychomotor regression / dementia / intellectual decline Frequent - Intracranial / cerebral calcifications - Seizures / epilepsy / absences / spasms / status epilepticus - Transient cerebral ischemia / stroke Occasional - Early death / lethality